HMG COA Reductase Inhibitors - Top 10 adverse events

The top 10 adverse events reported to the FDA FAERS database for HMG COA Reductase Inhibitors are Myalgia, Type 2 diabetes mellitus, Rhabdomyolysis, Pain in extremity, Muscle spasms, Arthralgia, Fatigue, Muscular weakness, Asthenia, and Drug interaction. The distribution of these adverse events among the drugs marketed in this drug group are shown in the graph below. The Proportional Reporting Ratio (PRR) of these adverse events among HMG COA Reductase Inhibitor drugs are also included to analyze the disproportional ratio. The data used in the calculation includes all adverse event reports submitted to FAERS for the HMG COA Reductase Inhibitors from 2004 Q1 to 2024 Q3. Further analysis is required to confirm the potential signal for any of these drug-adverse events.